Will I be able to exit airport during return trip with Schengen single entry visa?

I will be traveling through Schengen on a single(probably) entry Schengen visa.

My return trip leaves from Rome and has a long layover in Amsterdam, will I be able to exit the airport and see Amsterdam during this time? Or is my flight from Rome considered the exit from the Schengen zone even though it passes through another Schengen country? Is the visa marked as used when I leave Rome? Thanx