Flight search with NOT (region) as destination and/or origin?
Say you are willing to go almost anywhere, but you MUST be out of Schengen by a particular date. Or you have a warrant for your arrest in a particular country.
Several search engines allow "anywhere" or some entire country as destination, but is there one that allows you to specify where you WON'T go?
And/or to specify places you cannot start from.
Filtering or scrolling through the results isn't always practical when the first umpteen dozen pages are the ones that aren't useful. (Like Bermuda being part of UK or Guam being part of USA.)
Azuon was a good choice for a while, but it has been broken for at least two years. ("There are no flights for your criteria"—when the criteria is from North America to Taiwan or South Korea during the months of May and June!)
Best Answer
Google Flights allows one to search for flights on a map. You could enter "Spain" or "Europe" as destinations.
Having the results on a map allow for easy exclusion simply by only looking at areas of interest.
While not a perfect answer this is easier than looking at a plain list of flights to mixed locations.
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Answer 2
I don't know of a site that does what you want but using Kayak Explore (https://www.kayak.com/explore/) you can see a map with the prices displayed for a given date and can help you get out of the region for the lowest price
Answer 3
I find that this could fall under the category of "I want all destinations with flags that contain blue but don't have stripes".
Finding a public service that can do this is hard but that doesn't stop you from developing an app of your own that can do this.
There are a lot of Flight API's available and combining these with some geographic data (idk what you mean by "region") should be rather easy. This however requires some programming skills.
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